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The synergism between polysulfides and anesthetics

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

It may be concluded from these experiments that polysulfides of the thiuram group (antabuse, tetrathion, sodium dimethyl- and diethyldithiocarbamates) prolong and, in some cases also enhance the action of narcotics. Care must be exercised when prescribing sodium amytal, chloral hydrate, and urethane to alcoholics under treatment with antabuse. These narcotics must not be prescribed in cases of accidental poisoning by polysulfides of the thiuram group.

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Authors and Affiliations

  1. Department of Pharmacology of the Voronezh Medical Institute, Voronezh, USSR

    M. V. Korablev

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  1. M. V. Korablev
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Korablev, M.V. The synergism between polysulfides and anesthetics. Bull Exp Biol Med 48, 1503–1505 (1959). https://doi.org/10.1007/BF00792744

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  • DOI: https://doi.org/10.1007/BF00792744

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