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Immunohistochemical detection of the localization of melationin and N-acetylserotonin in enterochromaffin cells

  • Morphology and Pathomorphology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Melatonin synthesis was identified by an immunohistochemical method with specific antisera against melatonin and N-acetylserotonin in the enterochromaffin cells of the gastrointestinal tract. It is considered that enterochromaffin cells, together with the pinealocytes of the pineal gland and other cells synthesizing melatonin in the retina and cerebellum, form a group of melatonin-producing cells with an important role in the maintenance of homeostasis.

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Literature Cited

  1. N. T. Raikhlin and I. M. Kvetnoi, Dokl. Akad. Nauk SSSR,215, No. 3, 731 (1974).

    Google Scholar 

  2. N. T. Raikhlin and I. M. Kvetnoi, Byull. Éksp. Biol. Med., No. 8, 114 (1974).

    Google Scholar 

  3. N. T. Raikhlin, I. M. Kvetnoi, and V. N. Tolkachev, Dokl. Akad. Nauk SSSR,221, No. 1, 226 (1975).

    Google Scholar 

  4. N. T. Raikhlin and I. M. Kvetnoi, Usp. Sovrem. Biol.,79, No. 3, 444 (1975).

    Google Scholar 

  5. N. T. Raikhlin and I. M. Kvetnoi, Tsitologiya, No. 9, 1047 (1975).

    Google Scholar 

  6. N. T. Raikhlin, I. M. Kvetnoy (I. M. Kvetnoi), and V. N. Tolkachev, Nature255, 344 (1975).

    Google Scholar 

  7. A. M. Khelimskii, The Pineal Gland [in Russian], Moscow (1969).

  8. E. I. Chazov and V. A. Isachenko, The Pineal Gland: Its Place and Role in the System of Neuroendocrine Regulation [in Russian], Moscow (1974).

  9. J. Axelrod and H. Weissbach, J. Biol. Chem.,236, 211 (1961).

    Google Scholar 

  10. G. A. Bubenik, G. M. Brown, J. Uhlir, et al., Brain Res.,81, 233 (1974).

    Google Scholar 

  11. D. Cardinali and J. Rosner, Endocrinology,89, 301 (1971).

    Google Scholar 

  12. L. J. Grote and G. M. Brown, Can. J. Biochem.,52, 196 (1972).

    Google Scholar 

  13. V. Erspamer and B. Asero, Nature,169, 800 (1952).

    Google Scholar 

  14. J. Gaddum and N. J. Giarman, Brit. J. Pharmacol.,11, 88 (1956).

    Google Scholar 

  15. A. Lerner, J. Case, J. Takahashi, et al., J. Am. Chem. Soc.,80, 2587 (1958).

    Google Scholar 

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Authors
  1. N. T. Raikhlin
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  2. I. M. Kvetnoi
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  3. Z. G. Kadagidze
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  4. A. V. Sokolov
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Raikhlin, N.T., Kvetnoi, I.M., Kadagidze, Z.G. et al. Immunohistochemical detection of the localization of melationin and N-acetylserotonin in enterochromaffin cells. Bull Exp Biol Med 82, 1751–1754 (1976). https://doi.org/10.1007/BF00790407

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  • DOI: https://doi.org/10.1007/BF00790407

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