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Inhibitory action of neuraminidase ofVibrio cholerae in Rauscher mouse leukemia

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The inhibitory action of the neuraminidase ofVibrio cholerae in Rauscher mouse leukemia was studied. After treatment of the spleen cells of leukemic mice with neuraminidase in doses of 50 units/ml or more, the ability of these cells to induce leukemia when injected into BALB/c mice was inhibited significantly. Neraminidase in the above concentration, if given by repeated parenteral injection, had no therapeutic action in Rauscher leukemia.

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Barinskii, I.F., Kobrinskii, G.D. Inhibitory action of neuraminidase ofVibrio cholerae in Rauscher mouse leukemia. Bull Exp Biol Med 82, 1697–1699 (1976). https://doi.org/10.1007/BF00790389

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  • DOI: https://doi.org/10.1007/BF00790389

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