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Effect of levodopa on the healing of neurogenic degenerative lesions of the gastric mucosa in rats

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Neurogenic degeneration of the gastric mucosa was produced in rats by immobilizing the animals for 3h and by electrical stimulation. At the end of stimulation hemorrhagic erosions had developed in the gastric mucosa and they were still present 48 h later. Macroscopic and microscopic investigations showed that injections of levodopa into the rats in a dose of 10 mg/kg for 2 days after the end of stimulation accelerated the healing of hemorrhagic erosions of the mucosa.

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Zabrodin, O.N., Bertash, V.I. Effect of levodopa on the healing of neurogenic degenerative lesions of the gastric mucosa in rats. Bull Exp Biol Med 82, 1684–1686 (1976). https://doi.org/10.1007/BF00790385

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  • DOI: https://doi.org/10.1007/BF00790385

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