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Role of GABA and glycine in the formation of somato-sympathetic reflexes

  • Pharmacology
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Abstract

The action of strychnine and picrotoxin, synaptic antagonists of glycine and GABA, on the components of somato-sympathetic reflexes evoked by stimulation of cutaneous and intercostal muscular afferents was studied in experiments on intact or cordotomized cats. Evoked potentials were recorded in the white ramus communicans of the 3rd thoracic segment. Strychnine and picrotoxin produced different changes in the magnitude of the various components of the reflex, indicating differences in the localization of the inhibitory action of GABA and glycine in the central link of the somato-sympathetic reflex arc.

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Kovalev, G.V., Morozov, I.S. & Petrov, V.I. Role of GABA and glycine in the formation of somato-sympathetic reflexes. Bull Exp Biol Med 82, 1677–1680 (1976). https://doi.org/10.1007/BF00790383

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  • DOI: https://doi.org/10.1007/BF00790383

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