Skip to main content
SpringerLink
Log in

Relationship between structure, microcirculation, and tissue vascular permeability of the liver in experimental toxic hepatitis

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Biomicroscopic investigation of the liver showed that in experimental toxic hepatitis induced by heliotrine, very early and marked disturbances of the microcirculation arise, before injury to the parenchyma. Progression of the disturbances of the microcirculation and tissue vascular permeability, leading to hypoxia of the liver tissue and disturbance of liver metabolism, play a dominant role in the intensification of the pathomorphological changes and conversion of the acute pathological process in the liver into chronic.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature Cited

  1. N. Kh. Abdullaev, Pathochemistry and Pathogenetic Therapy of Chronic Hepatitis and Cirrhosis of the Liver [in Russian], Tashkent (1968).

  2. N. Kh. Abdullaev, Kh. Ya. Karimov, and P. I. Tashkhodzhaev, in: Proceedings of the 2nd International Congress of Pathophysiologists [in Russian], Prague (1975), p. 3.

  3. P. N. Aleksandrov and A. M. Chernukh, Byull. Éksp. Biol. Med., No. 8, 121 (1971).

    Google Scholar 

  4. Kh. Ya. Karimov and V. A. Akrovbyan, Pat. Fiziol., No. 5, 58 (1968).

    Google Scholar 

  5. Kh. Ya. Karimov and M. K. Irgashev, in: Collected Research Publications of Central Research Laboratories of Medical Colleges of Uzbekistan [in Russian], Vol. 2, Samarkand (1974), pp. 28–29.

  6. M. N. Khanin, Arkh. Pat., No. 6, 35 (1956).

    Google Scholar 

  7. M. N. Khanin and A. A. Yuldashev, Pat. Fiziol., No. 4, 60 (1970).

    Google Scholar 

  8. A. M. Chernukh and N. Ya. Kovalenko, Byull. Éksp. Biol. Med., No. 9, 117 (1970).

    Google Scholar 

  9. A. M. Chernukh and N. Ya. Kovalenko, Byull. Éksp. Biol. Med., No. 5, 12 (1973).

    Google Scholar 

  10. A. M. Chernukh, P. N. Aleksandrov, and O. V. Alekseev, The Microcirculation [in Russian], Moscow (1975).

  11. S. G. McClugage and R. S. McCuskey, Microvasc. Res.,3, 354 (1971).

    Google Scholar 

  12. A. M. Rappaport, Microvasc. Res.,6, 212 (1973).

    Google Scholar 

  13. A. M. Rappaport, M. Knoblauch, and R. G. Black, Ann. New York Acad. Sci.,170, 48 (1970).

    Google Scholar 

Download references

Authors
  1. N. Kh. Abdullaev
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. K. A. Zufarov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kh. Ya. Karimov
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Academician of the Academy of Sciences of the Uzbek SSR.

Departments of Pathophysiology and Histology, Tashkent Medical Institute. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 11, pp. 1300–1302, November, 1976.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Abdullaev, N.K., Zufarov, K.A. & Karimov, K.Y. Relationship between structure, microcirculation, and tissue vascular permeability of the liver in experimental toxic hepatitis. Bull Exp Biol Med 82, 1621–1625 (1976). https://doi.org/10.1007/BF00790366

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00790366

Key Words

Search

Navigation