Abstract
The effect of copper, manganese, and cobalt on the chemical sensitivity of interoceptors was studied in acute experiments on 82 cats. Injection of cuprous chloride was found to cause reversal of blood pressure and respiratory reflexes to acetylcholine, cobaltous chloride weakened these reflexes, whereas manganous chloride potentiated them. The changes observed in the interoceptive reflexes are considered to depend mainly on the direct action of the trace elements on interoceptor function.
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Pilipyuk, N.B. Effect of copper, manganese, and cobalt ions on chemical sensitivity of interoceptors. Bull Exp Biol Med 82, 1602–1604 (1976). https://doi.org/10.1007/BF00790360
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DOI: https://doi.org/10.1007/BF00790360