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The relationship between the localization of radiation injury and the functional state of an organ

Communication 2

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

An attempt was made to study the effect of increased diuresis, induced following irradiation, upon the morphology of the kidneys. Euphyllin was repeatedly administered to mice of the C57 lineage following general irradiation (apparatus RUM-3, voltage −180 kv, current −10 ma, filter −0.5 mm Cu+1 mm Al, intensity −45–48 r/m, dose −1,400 r). Euphyllin administration considerably prolonged the animals' life span and protected the kidneys from radiation injury. The effect of a diuretic is regarded by the authors as being due to the excretion of the toxic products of tissue disintegration (appearing as a result of the action of ionizing radiation).

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Authors and Affiliations

  1. Department of Pathological Anatomy of the Tomsk Medical Institute, Tomsk, USSR

    N. V. Sokolova & T. I. Gorshenina

Authors
  1. N. V. Sokolova
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  2. T. I. Gorshenina
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Sokolova, N.V., Gorshenina, T.I. The relationship between the localization of radiation injury and the functional state of an organ. Bull Exp Biol Med 50, 1125–1128 (1961). https://doi.org/10.1007/BF00788827

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  • DOI: https://doi.org/10.1007/BF00788827

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