Summary
In the majority of cases of protein sensitization in dogs, beginning from the 8th to the 12th day following the introduction of the first sensitizing dose, there was a general tendeccy of the blood bromine level to decrease. Besides, from the 18th to the 22nd day—the last days of sensitization—there was relative instability of the blood bromine level. Variations of the latter during anaphylactic shock were of a biphasic character, i.e., hyperbromemia at the onset of shock was replaced by gradual reduction of the bromine level which sometimes fell to marked hypobromemia. The latter was especially pronounced in animals which died within the first hour after the introduction of the booster of the serum.
No regular deviations in the blood bromine content were revealed in the postshock period.
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Tatarinov, I.S. Variations in the blood bromine level during sensitization, anaphylactic shock and the postshock period. Bull Exp Biol Med 45, 48–51 (1958). https://doi.org/10.1007/BF00785974
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DOI: https://doi.org/10.1007/BF00785974