Abstract
L-1210 and P-388 leukemic cells were incubated in three types of interferon: L-cell and two types of lymphocytic interferon (induced in lymphocytes of intact mice and lymphocytes taken from mice of the same strain on the 10th day after intraperitoneal injection of 5·107 L-1210 cells). Pseudointerferon obtained by a method similar to that used to obtain L-cell interferon, but without the virus induction, was used as the control. Cells incubated in interferon were found to be more sensitive to the action of antibodies than cells treated with pseudointerferon. Treatment of cells with lymphocytic interferon induced in lymphocytes of immune mice increased their sensitivity even more than cells treated with interferon obtained in intact lymphocytes.
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Skurkovich, S.V., Kalinina, I.A., Eremkina, E.I. et al. Increase in sensitivity of leukemic cells incubated in interferon to the action of immune serum. Bull Exp Biol Med 82, 1822–1824 (1976). https://doi.org/10.1007/BF00785707
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DOI: https://doi.org/10.1007/BF00785707