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Character of the stimulating action of antilymphocytic serum in the early stages of restoration of hematopoiesis in the spleen of radiation chimeras

  • Microbiology and Immunology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The object of this investigation, conducted on 236 BALB/c mice, was to study the effect of antilymphocytic serum (ALS) on the early stages of restoration of hematopoiesis in the spleen of radiation chimeras, having regard to the fact that ALS increases the number of macroscopic hematopoietic colonies. The results showed that this increase is connected with intensification of the first stage of restoration of hematopoiesis, i.e., with acceleration and intensification of the activation process of the reticular cells of the recipient's spleen.

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Literature Cited

  1. M. M. Nezdatnyi and K. K. Zaitseva, Dokl. Akad. Nauk SSSR,225, 981 (1975).

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  2. I. L. Chertkov, L. N. Lemeneva, and O. A. Mendelevich, Probl. Gematol., No. 1, 3 (1972).

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Zaitseva, K.K., Nezdatnyi, M.M. Character of the stimulating action of antilymphocytic serum in the early stages of restoration of hematopoiesis in the spleen of radiation chimeras. Bull Exp Biol Med 82, 1819–1821 (1976). https://doi.org/10.1007/BF00785706

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  • DOI: https://doi.org/10.1007/BF00785706

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