Skip to main content
SpringerLink
Log in

The effect of the magnesium-disodium salt of EDTA on experimental ventricular arrhythmias in dogs

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Experiments were staged on dogs with induced ventricular tachycardia. As shown, magnesium-disodium salt of EDTA had an antiarrhythmic effect. However, although in arrhythmia induced by ligature of the coronary artery this action was manifested only in some cases, in strophanthin intoxication MgNa2 EDTA had a constant distinct therapeutic effect.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature Cited

  1. I. N. Bel'gova, Farmakol. i Toksikol., 2, 239 (1961).

    Google Scholar 

  2. D. I. Zakutinskii and L. N. Selivanova, Med. prom. SSSR, 10, 48 (1958).

    Google Scholar 

  3. D. I. Semenov, Priroda, 8, 25 (1959).

    Google Scholar 

  4. L. J. Boyd and D. Scherf, Am. J. med. Sci. 1943, v. 206, p. 43.

    Google Scholar 

  5. N. E. Clarke, N. E. Clarke, and R. E. Mosher, Am. J. med. Sci. 1960, v. 239, p. 732.

    Google Scholar 

  6. B. D. Cohen, N. Spritz, G. Lubash, et al., Circulation, 1959, v. 19, p. 918.

    Google Scholar 

  7. C. D. Enselberg, H. G. Simmons, and A. A. Mintz, Am. Heart J. 1950, v. 39, p. 703.

    Google Scholar 

  8. A. S. Harris, et al., Am. J. Physiol. 1953, v. 172, p. 251.

    Google Scholar 

  9. J. R. Kitchell, L. E. Meltzer, and M. J. Seven, Progr. cardiovasc. Dis. 1961, v. 3, p. 338.

    Google Scholar 

  10. F. Mayr, A. Holasek, H. Flaschka, et al., Wien. med. Wschr. 1954, Bd. 104, S. 993.

    Google Scholar 

  11. E. Page and J. D. Real, Circulat. Res. 1955, v. 3, p. 501.

    Google Scholar 

  12. C. J. Rothberger and L. Zwillinger, Arch. exp. Path. Pharmak., 1936, Bd. 181, S. 301.

    Google Scholar 

  13. N. Sapeika, Arch. inst. Pharmacodyn. 1954, v. 97, p. 373.

    Google Scholar 

  14. P. W. Smith and E. H. Grinnell, Fed. Proc. 1955, v. 14, p. 387.

    Google Scholar 

  15. A. Soffer, T. Toribara, D. Moore-Jones, et al., Arch. intern. Med. 1960, v. 106, p. 824.

    Google Scholar 

  16. B. Surawicz, M. G. MacDonald, et al., Am. Heart J., 1959, v. 58, p. 493.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratory of Pharmacology, Khar'kov Research Chemo-Pharmaceutical Institute, Khar'kov, USSR

    E. I. Gendenshtein & L. A. Karskaya

Authors
  1. E. I. Gendenshtein
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. A. Karskaya
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gendenshtein, E.I., Karskaya, L.A. The effect of the magnesium-disodium salt of EDTA on experimental ventricular arrhythmias in dogs. Bull Exp Biol Med 54, 1252–1255 (1963). https://doi.org/10.1007/BF00785600

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00785600

Keywords

Search

Navigation