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The uridine diphosphoglucose content of leucocytes in healthy and in leukemic individuals

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

A study was made of the quantitative content of uridine diphosphoglucose (UDPG) and the rate of renewal of its glycoside component in the leucocytes of healthy individuals, and in patients with chronic myelosis, chronic lymphadenosis and polycythemia.

In healthy individuals and in patients with polycythemia, chronic myelosis and chronic lymphadenosis the UDPG content per 1 ml of leukocytes was found to amount to 44, 42, 72, and 34 micrograms respectively. In studying the rate of glucose component metabolism in UDPG it was revealed that within 30 min of incubation the specific radio activity of the UDPG glycoside and that of the medium glucose became entirely equivalent.

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Authors and Affiliations

  1. Biochemistry Laboratory, Leningrad Scientific-Research Institute of Blood Transfusion, Leningrad, USSR

    A. D. Vladimirova & I. F. Seitz

Authors
  1. A. D. Vladimirova
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  2. I. F. Seitz
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Vladimirova, A.D., Seitz, I.F. The uridine diphosphoglucose content of leucocytes in healthy and in leukemic individuals. Bull Exp Biol Med 58, 1189–1192 (1964). https://doi.org/10.1007/BF00785005

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  • DOI: https://doi.org/10.1007/BF00785005

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