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The effect of Pasteurella pestis toxin on the histamine-binding power of the blood of albino rats and guinea pigs

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Whole citrate blood of albino rats and guinea pigs produced a histaminopexic effect: there was no difference between the capacity of the blood of both species of animals to bind histamine. The histaminopexic effect of the blood showed a marked reduction after administration ofPast. pestis toxin to these animals. This effect was established 4 h and even 18 h after administration of the toxin. In experiments in vitro no depression of the histaminopexic effect of the blood by the toxin was noted.

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Authors and Affiliations

  1. Biochemical Laboratory, Irkutsk Plague Research Institute of Siberia and the Far East, Irkutsk, USSR

    I. V. Domaradskii & V. I. Krupenina

Authors
  1. I. V. Domaradskii
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  2. V. I. Krupenina
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Domaradskii, I.V., Krupenina, V.I. The effect of Pasteurella pestis toxin on the histamine-binding power of the blood of albino rats and guinea pigs. Bull Exp Biol Med 55, 518–520 (1964). https://doi.org/10.1007/BF00784406

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  • DOI: https://doi.org/10.1007/BF00784406

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