Summary
90 extracts of 39 different plants were investigated, regarding their cytotoxic effect on the cells of Ehrlich's ascites. This effect was found to be present in 15. Out of this number, 13 were tested in experimental treatment of Ehrlich's tumor. The extracts ofHippophae rhamnoides,Datisca cannabina andGleditsia triacanthos had pronounced retarding effect on the growth of this tumor.
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Additional information
From the Laboratory of Experimental Chemotherapy (Head-Prof. L. F. Larionov, Corresponding Member of the USSR Academy of Medical Sciences), the Laboratory of the Chemistry of Natural Substances (Head-Prof. G. P. Menshikov), the Institute for the Experimental Pathology and Therapy of Cancer (Director-N. N. Blokhin, Corresponding Member of the USSR Acad. of Med. Sci.) and from the Botanical Laboratory (Head-P. S. Massagetov) of the All-Union Chemical and Pharmaceutical Institute for Research
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Pukhalskaya, E.C., Petrova, M.F. & Massagetov, P.S. Plant extracts tested for cytotoxic and antitumorigenic action. Bull Exp Biol Med 43, 701–704 (1957). https://doi.org/10.1007/BF00784331
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DOI: https://doi.org/10.1007/BF00784331