Summary
Data are reported on the effect of subarachnoid injection of streptomycin on reflexes from the chemoreceptors of the carotid sinus, small intestine, and pericardium. Anesthetized cats were used in the experiments. Reflexes from the zones mentioned to chemical stimuli were profoundly depressed by streptomycin. Reflexes from mechanoreceptors, on the contrary, were almost unchanged. The excitability of the vasomotor center, when the tibial nerve was stimulated, remained quite high. It is concluded that streptomycin blocks directly the central portions of the afferent part of the chemoreceptor reflex arc.
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Kan, G.S. On the selective effect of some chemical irritants on reflexes from chemoreceptors. Bull Exp Biol Med 43, 683–687 (1957). https://doi.org/10.1007/BF00784327
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DOI: https://doi.org/10.1007/BF00784327