Summary
Experiments were made on guinea pigs. A study was made of the successive stages of resorption of transitional epithelium homografts, causing induction of osteogenesis in the recipeint's surrounding connective tissue. Bone induction does not prevent resorption of the homograft. Evidently massive epithelial destruction causes the appearance of substances active with respect to induction, which provoke intense osteogenesis.
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Petrakova, K.V., Fridenshtein, A.Y. Resorption of homografts of transitional epithelium inducing osteogenesis in the surrounding connective tissue. Bull Exp Biol Med 59, 194–197 (1965). https://doi.org/10.1007/BF00782729
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DOI: https://doi.org/10.1007/BF00782729