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The influence of bulbocapnine on behavior and on cerebral electrical activity in the cat

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Experiments were carried out on cats with electrodes implanted into the cortex and subcortex. A study was made of the effect produced by bulbocapnine on behavior and cerebral electrical activity. The motor effects included catalepsy and stupor, there were also sympathetic, parasympathetic, and emotional disturbances. The electrical changes occurred simultaneously in the cortex and the subcortex, and represented an activation. There was a marked increase in the cerebral responses to external stimuli, including rhythmic stimuli. We concluded that bulbocapnine exerts a central effect of a global nature and that both the sensory and motor elements of the cortex and subcortex are involved.

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Authors and Affiliations

  1. Institute of Psychiatry, AMN SSSR, Moscow

    E. M. Bogomolova & M. N. Konovalov

  2. Medico-Biological Department, All-Union Scientific Research Institute of Therapeutic and Aromatic Plants, Moscow

    E. M. Bogomolova & M. N. Konovalov

Authors
  1. E. M. Bogomolova
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  2. M. N. Konovalov
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Bogomolova, E.M., Konovalov, M.N. The influence of bulbocapnine on behavior and on cerebral electrical activity in the cat. Bull Exp Biol Med 59, 162–166 (1965). https://doi.org/10.1007/BF00782721

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  • DOI: https://doi.org/10.1007/BF00782721

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