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Effect of ionizing radiation on neurosecretion of hypothalamic nuclei

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The effect of ionizing radiation on the neurosectetion of the nuclei of the subthalamic area was investigated in rabbits subject to gamma-irradiation (sum total dose of 400 r).

An increase of neurosecretory substance was revealed 3 h after irradiation of cells of the supraoptic and paraventricular nuclei. There was a reduction of secretion on the 1st and 3rd days. Aminazine was administered to animals to ascertain the irradiation mechanism on the neurosecretory process. This agent eliminated the effect of increased secretion in the subthalamic nuclei, which was possibly associated with the blocking action of aminazine on the adrenergic systems of the reticular formation.

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Authors
  1. L. A. Andrianova
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Andrianova, L.A. Effect of ionizing radiation on neurosecretion of hypothalamic nuclei. Bull Exp Biol Med 59, 29–31 (1965). https://doi.org/10.1007/BF00782058

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  • DOI: https://doi.org/10.1007/BF00782058

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