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Excretion of typhoid fever antigen by the kidneys of dogs in the course of change in immunologic reactivity

  • Microbiology and Immunity
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

It was established that during immunization of dogs by the antigen of typhoid fever the latter was excreted by the kidneys.

The index of clearance of the antigen varies from 0.08 to 3.68 ml per minute, which constitutes from 0.11% to 2.5% of inulin clearance and from 0.41% to 3.96% of sodium thiosulfate clearance.

Excretion of typhoid fever antigen is not a process of simple filtration, but a complicated process in which both filtration and possibly reabsorption take part.

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Authors and Affiliations

  1. Department of Pathologic Physiology II, State Medical Institute, Moscow

    M. Khakberdyev

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  1. M. Khakberdyev
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Khakberdyev, M. Excretion of typhoid fever antigen by the kidneys of dogs in the course of change in immunologic reactivity. Bull Exp Biol Med 45, 483–487 (1958). https://doi.org/10.1007/BF00781261

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  • DOI: https://doi.org/10.1007/BF00781261

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