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The difference in the velocity of action of sodium amytal on the reflex arcs of the cervical and lumbar areas of the spinal cord

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The effect of sodium amytal on various reflex arcs of the spinal cord was studied in experiments on decerebrated spinal and intact cats.

It was established that the reflex arcs of the lumbar area of the spinal cord were more sensitive to the action of sodium amytal than those of the cervical area. The effect of this substance does not change when the lumbar portion of the sympathetic nervous system is removed as well as after section of the spinal cord at the level T7–8.

It was also demonstrated that different time is required for reestablishment of normal reflex activity in decerebrated, spinal and intact animals following administration of the same doses of sodium amytal.

On the basis of these experiments it is assumed that suprasegmental structures take part in this phenomenon.

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Authors and Affiliations

  1. Pathophysiologic Laboratory, The I.P. Pavlov Institute of Physiology, Acad. Sci. USSR, Leningrad

    O. B. Il'inskii

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  1. O. B. Il'inskii
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Deceased.

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Il'inskii, O.B. The difference in the velocity of action of sodium amytal on the reflex arcs of the cervical and lumbar areas of the spinal cord. Bull Exp Biol Med 45, 470–473 (1958). https://doi.org/10.1007/BF00781258

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  • DOI: https://doi.org/10.1007/BF00781258

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