Summary
It was demonstrated by experiments on rabbits than in 24 hours after the administration of erythrogenic or diphtheric toxin there is an increase of the nonspecific resistance to each of these toxins. Resistance which develops after the administration of erythrogenic toxin is connected with increased reactivity of the sympathetic system. This is shown by the rise of the blood adrenalin level. The latter prevents the development of collapse due to which the animals die during intoxication. This mechanism of physiological immunity is, evidently, the same in development of resistance to both toxins.
Similar content being viewed by others
Literature Cited
A.Ia. Alymov and D.F. Pletsityl, The Problem of Reactivity in Pathology [in Russian] (Moscow, 1954), pp. 9–18.
I.M. Liampert, Zhur. Mikrobiol., Epidemiol. i Immunobiol. No. 6 (1958).
F.A. Terent'ev and E.P. Stefanova, Zhur. Mikrobiol., Epidemiol. i Immunobiol. No. 2, 20–24 (1954).
G. Dallderf, S.M. Gohen and J.M. Coffey, J. Immunol. 56, 3, 295–300 (1947).
G.B. Edsall, in the book: Annual Review of Microbiology 9 (Stanford, 1955), pp. 347–368.
C.L. Larson, J.F. Bell and C.R. Owen, J. Immunol. 73, 4, 221–225 (1954).
D. Rowley, Lancet 1, 232–234 (1955).
D.R. Wharton and H.J. Creech, J. Immunol. 62, 2, 135–153 (1949).
H.D. Wright, J. Pathol. and Bacteriol. 30, 185–252 (1927).
Author information
Authors and Affiliations
Additional information
Submitted by Active Member Acad. Med. Sci. USSR G.V. Vygodchikov
Rights and permissions
About this article
Cite this article
Liampert, I.M., Levina, T.A. The nonspecific character of resistance arising after parenteral injection of erythrogenic toxin. Bull Exp Biol Med 45, 442–444 (1958). https://doi.org/10.1007/BF00781252
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00781252