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A biochemical analysis of biological preparations stimulating regeneration of the myocardium in rats

  • Biochemistry and Biophysics
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Bulletin of Experimental Biology and Medicine Aims and scope

Summary

For stimulation of regeneration of rat's myocardium the authors used a hydrolyzate and an extract of rat's heart. It was shown by the method of electrophoresis on paper that the hydrolyzate consists of 2 components similar by their motility to the albumin, and γ-globulin of the blood serum of rats. The extract contains 3 components similar by their motility to the albumin, α2- and γ-globulin of the blood serum of rats. The chromatographic analysis of the free amino acids of the hydrolyzate demonstrated the presence of arginine, lysine asparaginic acid, glycine, glutamic acid, alanine, proline, tyrosine, valine, phenylalanine and leucine. The same amino acids except arginine, proline and tyrosine were revealed in the extract. The quantity of nitrogen, the dry weight and pH were also determined in the preparations. We consider that proteins, nucleoproteids and the products of their disintegration comprise the active part of the preparation.

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Authors and Affiliations

  1. A. N. Severtsov Institute of Animal Morphology of the AN SSSR, Moscow

    V. L. Mant'eva

Authors
  1. V. L. Mant'eva
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Mant'eva, V.L. A biochemical analysis of biological preparations stimulating regeneration of the myocardium in rats. Bull Exp Biol Med 47, 704–707 (1959). https://doi.org/10.1007/BF00781225

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  • DOI: https://doi.org/10.1007/BF00781225

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