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The conditions for and the histochemical characteristics of osteogenic activity of transitional epithelium in grafts

  • Experimental Biology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Comparative histological and histochemical (alkaline phosphatase, polysaccharides) study of transitional epithelium transplants was conducted in guinea pigs and rabbits. It was demonstrated that the osteogenetic effect of transitional epithelium on the connective tissue is associated with the penetration into it of the polysaccharide metabolism intermediate products from the epithelium. High activity of alkaline phosphatase is revealed in the subepithelial connective tissue independent of the presence or absence of osteogenesis. Adefinite level of epithelial differentiation is necessary for the secretion of the osteogenetic factors into the underlying tissue, this level depending on the condition of connective tissue around the transplant.

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Fridenshtein, A.Y. The conditions for and the histochemical characteristics of osteogenic activity of transitional epithelium in grafts. Bull Exp Biol Med 47, 514–519 (1959). https://doi.org/10.1007/BF00779638

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  • DOI: https://doi.org/10.1007/BF00779638

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