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Problem concerning structure of saurine, a sesquiterpenic lactone from Saussurea pulchella Fisch

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Pharmaceutical Chemistry Journal Aims and scope

Conclusions

  1. 1.

    It was shown that the actual empirical formula of saurine is C19H22O6·H2O.

  2. 2.

    Two possible structural formulas of saurine (Ia and Ib) are proposed. The formulas were confirmed by the NMR spectra and mass spectra.

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Literature cited

  1. L. E. Kushnir and A. D. Kuzovkov, The Chemistry of Natural Compounds [in Russian], No. 4 (1966), p. 245.

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  2. A. Bellamy, Infrared Spectra of Complex Molecules [Russian translation], Moscow (1963), p. 269.

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The elemental analysis was run by E. A. Nikonova and E. A. Plokhova. M. E. Perel'son and A. A. Kir'yanov ran the IR spectra on a UR-10 instrument. The NMR spectra were run on a JNM-4H-100 instrument in the physicochemical methods of analysis laboratory (Prof. Yu. N. Sheinker director) of the S. Ordzhonikidze All-Union Research Pharmaceutical Chemistry Institute, The mass spectra were run on the MX-1303 instrument by V. M. Bochkarev. The authors thank K. K. Pivnitskii for his help in interpreting the NMR spectra.

Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 12, pp. 21–29, December, 1968.

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Kushnir, L.E., Kuzovkov, A.D. Problem concerning structure of saurine, a sesquiterpenic lactone from Saussurea pulchella Fisch. Pharm Chem J 2, 671–677 (1968). https://doi.org/10.1007/BF00763331

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  • DOI: https://doi.org/10.1007/BF00763331

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