Conclusions
The reaction of 2-mercapto- and 5,6-dimethyl-2-mercaptobenzimidazoles with ethylene chloro (bro o)hydrins and 1,2-dichloro(dibromo)ethanes was studied. With dihaloethanes, the process proceeds in two directions, formation of thiazolino(3,2-a)benzimidazoles and 1,2-di-(2′-mercaptobenzimidazolyl) ethanes. Thiazolino(3,2-α)benzimidazole and several of its derivatives were synthesized by cyclization of 2-(β-chloroethyl)mercapto- and 1-(β-chloromethyl)-2-mercaptobenzimidazoles.
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Communication XLII.
Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 10, pp. 18–21, October, 1968.
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Krasovskii, A.N., Kochergin, P.M. Investigations in the imidazole series. Synthesis of thiazolino-(3,2-α) benzimidazole and several of its derivatives. Pharm Chem J 2, 545–548 (1968). https://doi.org/10.1007/BF00759630
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DOI: https://doi.org/10.1007/BF00759630