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Developmental genetic studies of aminopeptidases inDrosophila melanogaster

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TheLap-D locus ofDrosophila melanogaster was investigated. The mode of inheritance of the alleles at this locus was confirmed and a new allele was discovered. The enzymes are not exclusively “pupal” enzymes but are found throughout the life cycle. Amino acid naphthylamides other than leucine naphthylamide were found to be effective substrates for these enzymes. It is suggested, therefore, that the restrictive designation “leucine aminopeptidase” be abandoned in favor of the more general amino acid naphthylamidase or aminopeptidase.

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Communicated by E. Hadorn

This work was supported by the U. S. Atomic Energy Commission under contract No. AT (11-1) 1338.

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Sakai, R.K., Tung, D.A. & Scandalios, J.G. Developmental genetic studies of aminopeptidases inDrosophila melanogaster . Molec. Gen. Genet. 105, 24–29 (1969). https://doi.org/10.1007/BF00750312

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  • DOI: https://doi.org/10.1007/BF00750312

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