References
Boyd M.R. (1989) ‘Status of the NCI preclinical antitumor drug discovery screen’, Principle & Practice of Oncology 3, 1–12.
Shoemaker R.H., Wolpert-DeFilippes M.K., Kern D.H. et al. (1985) ‘Application of a human tumor colony-forming assay to new drug screening’, Cancer Research 45, 2145.
Alley M.C., Scudiero D.A., Monks A. et al., (1988) ‘Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazoliys assay’, Cancer Research 30, 11.
D'Incalci M., Balconi G., Broggini M., Colombo M., et al. (1989), Problems in the design of anticancer agents’, Cancer Surveys 8, 535–555.
Broggini M., Ponti M., Ottolenghi S., D'Incalci M., et al. (1989) ‘Distamycins inhibit the binding of OTF-1 and NFE-1 transfactors to their conserved DNA elements’, Nucleic Acid Research 17, 1051–1059.
D'Incalci M., Citti L., Taverna P., Catapano C.V. (1988) ‘Importance of the DNA repair enzyme O6-alkylguanine alkyltransferase (AT) in cancer chemotherapy’, Cancer Treatment Reviews 15, 279–292.
Pegg A.E. (1990) ‘Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents, Cancer Research 50, 6119–6129.
Balconi G., Broggini M., Erba E., D'Incalci M., Colombo N., Bertolero F., (1988) ‘Human ovarian tumors in primary culture: growth, characterization and initial evaluation of the response to cisplatinum treatment in vitro. International Journal of Cancer 41, 809–818.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
D'Incalci, M., Balconi, G., Broggini, M. et al. Notes on the use of in vitro systems to investigate the activity and the mechanism of action of antineoplastic agents. Cytotechnology 5 (Suppl 1), 15–18 (1991). https://doi.org/10.1007/BF00736797
Issue Date:
DOI: https://doi.org/10.1007/BF00736797