Summary
Fibrous neuroglia has been studied by immunofluorescence with GFA protein antibodies in the spinal cord of mutant mice with deficient myelination: quaking and jimpy. In both these mutants a well formed astrocytic framework was observed in the non-myelinated white matter, indicating that the arrest of myelination in quaking and jimpy mice is associated with defects of the oligodendroglial cell line, rather than with an abnormality of glioblast differentiation.
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Bignami, A., Dahl, D. Glial fibrillary acidic protein in mutant mice with deficiency of myelination: Quaking and jimpy. Acta Neuropathol 28, 269–272 (1974). https://doi.org/10.1007/BF00719032
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DOI: https://doi.org/10.1007/BF00719032