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Syntheses of 2-oxabicyclo[4.10.0]hexadec-1(6)-ene from cyclododecanone

  • Organic Chemistry
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Russian Chemical Bulletin Aims and scope

Abstract

Two methods for the synthesis of 2-oxabicyclo[4.10.0]hexadec-1(6)-ene from cyclododecanone have been suggested. The most convenient method involves the preparation of 2-(3-tert-butoxypropyl)cyclododecanone by phase-transfer catalyzed alkylation of cyclododecanone with l-bromo-3-tert-butoxypropane followed by removal of the protectingtert-butyl group and elimination of water.

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Authors and Affiliations

  1. A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 ul.Vavilova, 117813, Moscow, Russian Federation

    L. I. Zakharkin & I. M. Churilova

Authors
  1. L. I. Zakharkin
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  2. I. M. Churilova
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Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 4, pp. 659–661, April, 1994.

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Zakharkin, L.I., Churilova, I.M. Syntheses of 2-oxabicyclo[4.10.0]hexadec-1(6)-ene from cyclododecanone. Russ Chem Bull 43, 608–611 (1994). https://doi.org/10.1007/BF00699833

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  • DOI: https://doi.org/10.1007/BF00699833

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