Summary
Lamellar bodies are stacks of parallel cisternae of approximately regular spacing derived from ergastoplasm. Their occurrence was studied in various nervous and epithelial cells of different animal species in both normal and diseased subjects. This organelle appears to be, at least for some cell types, a normal cytoplasmic feature. The number of lamellar bodies increases in some pathologic conditions and when the cell metabolism is elevated.
References
Cameron, A. M., Conroy, J. D.: Rabies-like inclusions associated with a neoplastic reticulosis in a dog. Vet. Pathol.11, 29–37 (1974)
Erler, G., Baumann, R. P., Wegmann, W.: Rhabdomyosarcome alvéolaire ou histiocytose maligne? Schweiz Med. Wochenschr.109, 411 (1979)
Furth, J., Clifton, K. H., Gadsden, E. L., Buffet, R. F.: Dependent and autonomous mammotropic pituitary tumours in rats; their somatotropic features. Cancer Res.16, 608–616 (1956)
Gessaga, E. C.: Licht-und elektronenmikroskopische Befunde am Zentralnervensystem eines an Rabies verstorbenen 36 jährigen Mannes. Schweiz. Med. Wochenschr.108, 506 (1978)
Herndon, R. M.: Lamellar bodies, an unusual arrangement of the granular endoplasmic reticulum. J. Cell Biol.20, 338–342 (1964)
Kelley, R. O.: Ultrastructural comparison of paired cisternae in leukemic and mesenchymal cells during mitosis. Anat. Rec.171,559–566 (1971)
Kovacs, K., Horvath, E., Bilbao, J. M., Ilse, R. G.: Anulatae lamellae in spontaneous prolactin cell adenomas of the rat pituitary. Anat. Anz.141, 59–65 (1977)
Le Beux, Y. J.: Subsurface cisterns and lamellar bodies: Particular forms of the endoplasmic reticulum in neurons. Z. Zellforsch.133, 327–352 (1972)
Peters, A., Palay, S. L., Webster, H.: The axon. In: The fine structure of the nervous system: The neurons and the supporting cells, pp. 406. Philadelphia, London, Toronto: Saunders 1976
Rohkamm, R.: Degeneration and regeneration in neurons of the cerebellum. Adv. Anat. Embryol. Cell Biol.53, 1–118 (1975)
Rossi, G. L.: Simple apparatus for perfusion fixation for electron microscopy. Experientia31, 998 (1975)
Schultz, R. L., Karlsson U.: Fixation of the central nervous system for electron microscopy by aldehyde perfusion. II. Effect of osmolarity, pH of perfusate, and fixative concentration. J. Ultrastruct. Res.12, 160–186 (1965)
Yu, M. C., Bakay, L., Lee, J. C.: Ultrastructure of the central nervous system after prolonged hypoxia. I. Neuronal alterations. Acta Neuropathol. (Berl.)22, 222–234 (1972)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Bestetti, G., Rossi, G.L. The occurrence of cytoplasmic lamellar bodies in normal and pathologic conditions. Acta Neuropathol 49, 75–78 (1980). https://doi.org/10.1007/BF00692224
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00692224