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Hydrolytic enzymes in meningiomal subtypes

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Summary

Estimation of activity of five hydrolytic enzymes was made in four histologically different types of human meningiomas derived from surgery. The hydrolytic enzymes examined in 13 tumors included four lysosomal enzymes: β-glucuronidase, N-acetyl-β-d-glucosaminidase (hexosaminidase), β-galactosidase, and acid phosphatase. The fifth enzyme studied was alkaline phosphatase. The one papillary-type meningioma examined appeared to contain generally greater activities of the lysosomal enzymes than the other tumor types. Alkaline phosphatase was decidedly greater in transitional type meningiomas. The correlation of histological types with alkaline phosphatase activity is discussed with regard to previous observations.

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Ramsey, R.B., Fredericks, M., Crafts, D.C. et al. Hydrolytic enzymes in meningiomal subtypes. Acta Neuropathol 49, 63–65 (1980). https://doi.org/10.1007/BF00692221

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