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Ultrastructure of Opalski cells cultured in vitro

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Summary

The object of the present study was to analyse the ultrastructure of Opalski cells, obtained in tissue culture according to the method described by Mossakowskiet al. (1970). The electron microscopic picture of the Opalski cells was characterized by scanty endoplasmic reticulum and Golgi apparatus and a greatly reduced number of mitochondria, as compared with glial cells cultured in vitro. Their cytoplasm contained two types of spherical bodies, one of which corresponded to lysosome-like bodies; the second one, in the authors' opinion, represented an accumulation of mucopolysaccharide substances.

The ultrastructural picture of Opalski cells corresponded well with their previously described histochemical properties.

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Authors and Affiliations

  1. Experimental and Clinical Medical Research Centre of Polish Academy of Sciences, 3 Dworkowa Str., Warszawa, Poland

    M. J. Mossakowski, J. W. Borowicz, Z. Kraśnicka & J. Gajkowska

Authors
  1. M. J. Mossakowski
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  2. J. W. Borowicz
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  3. Z. Kraśnicka
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  4. J. Gajkowska
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Additional information

Work was partially supported by P. L. 480 grant, Public Health Service USA. Agreement 227704.

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Mossakowski, M.J., Borowicz, J.W., Kraśnicka, Z. et al. Ultrastructure of Opalski cells cultured in vitro. Acta Neuropathol 19, 301–306 (1971). https://doi.org/10.1007/BF00692150

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  • DOI: https://doi.org/10.1007/BF00692150

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