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Central pontine myelinolysis

A case report

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Summary

A case of central pontine myelinolysis, the 19th so far published or communicated, is described in a Jewish woman of Yemenite extraction who had suffered for 12 years prior to her death from a mental condition diagnosed as chronic schizophrenia. Anatomo-pathologically the pontine lesion was similar to those described in previous cases, except that in this case there were “pools” of mucoid material present in it. The lesion developed in the absence of alcoholism and in association with a state of general dehydration and electrolyte imbalance in the patient.

Zusammenfassung

Ein Fall von zentraler pontiner Myelinose — der 19. bisher veröffentlichte oder mitgeteilte — wird beschrieben: eine aus dem Yemen stammende Jüdin litt 12 Jahre vor ihrem Tod an einer Nervenkrankheit, die als chronische Schizophrenie diagnostiziert wurde. Anatomisch-pathologisch war die Brückenläsion ähnlich der in den früheren Fällen beschriebenen, mit der Ausnahme, daß Anhäufungen von mucoidem Material vorgefunden wurden. Die Läsion entwickelte sich bei dieser Patientin — ohne Alkoholmißbrauch — in Zusammenhang mit einem Zustand von generellem Flüssigkeitsverlust und Elektrolytgleichgewichtsstörung.

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Behar, A., Bental, E. & Aviram, A. Central pontine myelinolysis. Acta Neuropathol 3, 343–350 (1964). https://doi.org/10.1007/BF00691842

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