Summary
The cases are described of two sibs who developed hepatic cirrhosis in early infancy, accompanied by profound mental retardation. Post mortem in one sib there were multiple foci of demyelination with abundant cellular infiltration, scattered throughout the brain. These unusual pathological changes are briefly commented.
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References
Plum, F., Hindfelt, B.: The neurological complications of liver diseases. In: Vinken, P. J., Bruyn, G. W. (eds.). Handbook of clinical neurology, Vol. 27, pp. 349–377. Amsterdam: North-Holland 1976
Blackwood, W., Buxton, P. H., Cumming, J. N.: Diffuse cerebral degeneration in infancy. Arch. Dis. Child.38, 193–204 (1963)
Welfring, K. W., Lamvick, V.: Familial progressive poliodystrophy with cirrhosis of the liver. Acta. Paediatr. Scand.56, 295–300 (1963)
Huttenlocher, P. R., Solitaire, G. B., Adams, G.: Infantile diffuse cerebral degeneration with hepatic cirrhosis. Arch. Neurol.33, 186–192 (1976)
Victor, M., Adams, R. D., Cole, M.: Acquired (non-Wilsonian) type of chronic hepato-cerebral degeneration. Medicine (Baltimore)44, 345–396 (1965)
Jellinger, K., Riederer, P., Kleinberger, G., Wukelich, S., Kothbauer, P.: Brain monoamines in human hepatic encephalopathy. Acta. Neuropathol. (Berl.)43, 63–68 (1978)
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Jervis, G.A. Encephalopathy in infantile hepatic cirrhosis. Acta Neuropathol 48, 73–75 (1979). https://doi.org/10.1007/BF00691795
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DOI: https://doi.org/10.1007/BF00691795