Skip to main content
Log in

Wernicke's encephalopathy in infancy

Development during parenteral nutriton

  • Short Original Communications
  • Published:
Acta Neuropathologica Aims and scope Submit manuscript

Summary

Wernicke's encephalopathy documented by characteristic involvement of the mammillary bodies developed in a premature infant during parenteral nutrition. This case illustrates the need for thiamine supplementation in seriously ill patients with inadequate intake of the vitamin.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Bamji, M. S.: Enzymic evaluation of thiamine, riboflavin, and pyridoxine status of parturient women and their newborn infants. Br. J. Nutr.35, 259–265 (1976)

    Google Scholar 

  • Baughman, F. A., Papp, J. P.: Wernicke's encephalopathy with intravenous hyperalimentation: Remarks on similarities between Wernicke's encephalopathy and the phosphate depletion syndrome. Mt. Sinai J. Med. N. Y.43, 48–52 (1976)

    Google Scholar 

  • Blennow, G.: Wernicke encephalopathy following prolonged artificial nutrition. Am. J. Dis. Child.129, 1456 (1975)

    Google Scholar 

  • Campbell, A. C. P., Russell, W. R.: Wernicke's encephalopathy: The clinical features and their probable relationship to vitamin B deficiency. Q. J. Med.10, 41–51 (1941)

    Google Scholar 

  • Cochrane, W. A., Collins-Williams, C., Donohue, W. L.: Superior hemorrhagic polioencephalitis (Wernicke's disease) occurring in an infant — probably due to thiamine deficiency from use of a soya bean product. Pediatrics28, 771–777 (1961)

    Google Scholar 

  • Cravioto, H., Korein, J., Silberman, J.: Wernicke's encephalopathy. Arch. Neurol.4, 510–519 (1961)

    Google Scholar 

  • Davis, R. A., Wolf, A.: Infantile beriberi associated with Wernicke's encephalopathy. Pediatrics21, 409–420 (1958)

    Google Scholar 

  • Feigin, I., Wolf, A.: A disease in infants resembling chronic Wernicke's encephalopathy. J. Pediatr.45, 243–263 (1954)

    Google Scholar 

  • Gullotta, F.: Encefalopatia di Wernicke in bambini cardiopatici. Acta Neurol. (Napoli)31, 71–73 (1976)

    Google Scholar 

  • Kramer, J., Goodwin, J. A.: Wernicke's encephalopathy. Complication of intravenous hyperalimentation. JAMA238, 2176–2177 (1977)

    Google Scholar 

  • Montpetit, V. J. A., Anderman, F., Carpenter, S., Fawcett, J. S., Zborowska-Sluis, D., Giberson, H. R.: Subacute necrotizing encephalomyelopathy: A review and study of two families. Brain94, 1–30 (1971)

    Google Scholar 

  • Nadel, A. M., Burger, P. C.: Wernicke encephalopathy following prolonged intravenous therapy. JAMA235, 2403–2405 (1976)

    Google Scholar 

  • Peña, C. E.: Wernicke's encephalopathy: Report of seven cases with severe nerve cell changes in mammillary bodies. Am. J. Clin. Pathol.51, 603–609 (1969)

    Google Scholar 

  • Tanaka, T.: So-called breast milk intoxication. Am. J. Dis. Child.47, 1286–1298 (1934)

    Google Scholar 

  • Thiele, V. F., Brin, M., Dibble, M. V.: Preliminary biochemical findings in Negro migrant workers at King Ferry, New York. Am. J. Clin. Nutr.21, 1229–1238 (1968)

    Google Scholar 

  • Victor, M., Adams, R. D., Collins, G. H.: The Wernicke-Korsakoff syndrome: A clinical and pathological study of 245 patients, 82 with post-mortem examination. Philadelphia: Davis 1971

    Google Scholar 

  • Ziporin, Z. Z., Nunes, W. T., Powell, R. C., Waring, P. P., Sauberlich, H. E.: Excretion of thiamine and its metabolites in the urine of young adult males receiving restricted intakes of the vitamin. J. Nutr.85, 287–296 (1965)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Meyers, C.C., Schochet, S.S. & McCormick, W.F. Wernicke's encephalopathy in infancy. Acta Neuropathol 43, 267–269 (1978). https://doi.org/10.1007/BF00691590

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00691590

Key words

Navigation