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Beitrag zur Pathogenese der Gefäßthromben bei hämatogener Candidainfektion des ZNS

Contribution to the pathogenesis of thrombosis in haematogenic infection of the CNS by Candida albicans

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Summary

In haematogenic Candida infection of the CNS pseudohyphae are first found in capillaries from which they grow into the surrounding tissue. From here they involve the outer parts of the vessel walls. The lamina elastica interna first embarrasses their growth, but finally they penetrate into the tunica intima and cause a lesion that leads to thrombosis. The possibility of fungi spread via the vessels this way is mentioned. The affinity of Candida albicans for the vessel walls is discussed.

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Authors and Affiliations

  1. Neuropathologische Abteilung, Max-Planck-Institut für Psychiatrie, Kraepelinstraße 2, D-8000, München

    F. H. Stefani & W. Issel

Authors
  1. F. H. Stefani
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  2. W. Issel
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Stefani, F.H., Issel, W. Beitrag zur Pathogenese der Gefäßthromben bei hämatogener Candidainfektion des ZNS. Acta Neuropathol 19, 70–74 (1971). https://doi.org/10.1007/BF00690955

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  • DOI: https://doi.org/10.1007/BF00690955

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