Skip to main content
Log in

Astroblastoma revisited: A report of three cases

  • Original Works
  • Published:
Acta Neuropathologica Aims and scope Submit manuscript

Summary

The very existence of astroblastoma has been a question of considerable controversy, although there appears now to be sufficient documentation to establish it as a tenable entity. Due to the rarity of this tumor, little information exists in the literature as to its natural history, efficacy of therapy and its pathological and radiological appearance. We report three cases of astroblastoma, describing their natural history, the response to therapeutic interventions and their light microscopic, ultrastructural and immunohistochemical characteristics.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Bailey P, Bucy P (1930) Astroblastomas of the brain. Acta Psychiatr Scan 5: 439–461

    Google Scholar 

  • Bailey P, Cushing H (1924) Tumors of the glioma group. Lippincott, Philadelphia, pp 175

    Google Scholar 

  • Bonnin JM, Rubinstein LJ (1984) Immunohistochemistry of central nervous system tumors. Its contribution to neurosurgical diagnosis. J Neurosurg 60: 1121–1133

    Google Scholar 

  • Elvidge A, Penfield W, Cone W (1935) Gliomas of central nervous system; study of 210 verified cases. Assoc Res Nerv Ment Dis 16: 107–181

    Google Scholar 

  • Eng LF, Rubinstein LJ (1978) Contribution of immunohistochemistry to diagnostic problems of human cerebral tumors. J Histochem Cytochem 26: 513–522

    Google Scholar 

  • Eng LF, Vanderhaeghen JJ, Bignami A, Gerstl B (1971) An acidic protein isolated from fibrous astrocytes. Brain Res 28: 351–354

    Google Scholar 

  • Hulstrom D, Malmgren L, Gilstring D, Olsson Y (1983) FITC-Dextrans as tracers for macromolecular movements in the nervous system. Acta Neuropathol (Berl) 59: 53–62

    Google Scholar 

  • Hwang TL, Borit A (1982) Rosenthal fibers in glioblastoma multiforme. Acta Neuropathol (Berl) 57: 230–232

    Google Scholar 

  • Kubota T, Hirano A, Sato K, Yamamoto S (1985) The fine structure of astroblastoma. Cancer 55: 745–750

    Google Scholar 

  • Roessmann U, Velasco ME, Gambetti P, Autilio-Gambetti L (1983) Vimentin intermediate filaments are increased in human neoplastic astrocytes. J Neuropathol Exp Neurol 42: 309 (Abstr.)

    Google Scholar 

  • Rubinstein LJ (1970) Tumors of the central nervous system. AFIP, Washington DC, pp 50–52

    Google Scholar 

  • Scharenberg K, Liss L (1969) Neuroectodermal tumors of the central and peripheral nervous system. Williams and Wilkins, Baltimore, pp 17–29

    Google Scholar 

  • Velasco ME, Dahl D, Roessman U, Gambetti P (1980) Immunohistochemical localization of glial fibrillary acidic protein in human glial neoplasms. Cancer 45: 484–494

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hoag, G., Sima, A.A.F. & Rozdilsky, B. Astroblastoma revisited: A report of three cases. Acta Neuropathol 70, 10–16 (1986). https://doi.org/10.1007/BF00689508

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00689508

Key words

Navigation