Summary
In a 57-year-old male patient meningitic symptoms occurred. CSF cytology exhibited carcinoma cells, thus establishing the diagnosis of carcinomatous meningeosis. The primary site of the tumor or metastases were not detected intra vitam. The autopsy revealed a malignant thymoma with an exclusive metastatic participation of the leptomeninges except for some few regional lymph nodes. Cerebral metastases of malignant thymoma is an extremely rare condition.
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References
Batata MA, Martini N, Huvos AG, Aguilar RI, Beattie EJ (1974) Thymomas, clinicopathologic features, therapy, and prognosis. Cancer 34:389–396
Danisch F, Nedelmann E (1928) Bösartiges Thymom bei einem 3 1/2jährigen Kind mit eigenartiger Metastasierung ins Zentralnervensystem. (Zugleich ein Beitrag zur Klinik und pathologischen Anatomie der Geschwulstmetastasierung auf dem Liquorwege.) Virchows Arch [Pathol Anat] 268:492–514
Gray GF, Gukowski WT (1979) Thymoma. A clinicopathological study of 54 cases. Am J Surg Pathol 3:235–249
Lattes R (1962) Thymoma and other tumors of the thymus. An analysis of 107 cases. Cancer 15:1224–1260
Mac Donald J, Parker JC, Brown S, Page LK, Wolfe DE (1978) Cerebral metastasis from a malignant thymoma. Surg Neurol 9:58–60
Otto HF (1984) Pathologie des Thymus. In: Doerr W, Seifert G, Uehlinger E (Hrsg) Spezielle pathologische Anatomie, Bd 17. Springer, Berlin Heidelberg New York Tokyo, S 116–197
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Kleinert, R., Walter, G.F. & Kleinert, G. Carcinomatous meningeosis as exclusive metastasizing pattern in a malignant thymoma. Acta Neuropathol 67, 329–331 (1985). https://doi.org/10.1007/BF00687821
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DOI: https://doi.org/10.1007/BF00687821