Summary
Ultrastructural study of peripheral nerves in a case of Landry-Guillain-Barré syndrome dying during early recovery phase reveals characteristic findings which are inter preted as being regenerative changes. Layers of compact vesicles and tubules are seen around each axon and coalescence of these vesicles appears to be followed by formation of myelin lamella. There is suggestive evidence that the vesicles may be produced by the endoplasmic reticulum of the axon.
Zusammenfassung
Die ultrastrukturelle untersuchung der peripheren Nerven eines Falles von Landry-Guillain-Barré Syndrom, der während einer kurzen Erholungsphase starb, ergibt charakteristische Befunde, die als regenerative Veränderung gedeutet werden. Um jedes Axon sieht man geschlossene Lagen von Vesikeln und Tubuli; das Verschmelzen dieser Vesikeln scheint von der Bildung der Myelinlamellen gefolgt zu werden. Es drängt sich die Annahme auf, daß die Vesikeln vom endoplasmischen Reticulum der Axone gebildet werden.
References
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Liu, H.M. Ultrastructure of remyelination of peripheral nerves in Landry-Guillain-Barré syndrome. Acta Neuropathol 16, 262–265 (1970). https://doi.org/10.1007/BF00687365
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DOI: https://doi.org/10.1007/BF00687365