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The permanent long-term effects of postnatal X-irradiation on the rat cerebellum

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Summary

The heads of seven day old rats were irradiated with 600 rads. The permanent long-term effects on the cerebellum were examined histologically seven months after irradiation. The effects of radiation were not homogenous, with selective loss or abnormal distribution of granular cells and disorientation of Purkinje cells. The possible reasons for these modifications in cerebellar structure are discussed.

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Hopewell, J.W. The permanent long-term effects of postnatal X-irradiation on the rat cerebellum. Acta Neuropathol 27, 163–169 (1974). https://doi.org/10.1007/BF00687166

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