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Central nervous system and skeletal muscle involvement in systemic candidiasis

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Summary

Two necropsy cases of systemicCandida albicans infection with involvement of the kidney, lung and brain are reported. Both patients died from renal failure. In the brain there was a miliary spread of microabscesses and granuloma-like lesions, and Candida was evident within both types of lesion. In case 2, there was additional involvement of skleletal muscle and diaphragma with focal-grouped and single-scattered necrotic muscle fibres and small granulomas containing fungus elements accompanied by mild neurogenic atrophy of skeletal muscle due to “uremic” neuropathy.

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Jellinger, K., Bankl, H. Central nervous system and skeletal muscle involvement in systemic candidiasis. Acta Neuropathol 18, 257–261 (1971). https://doi.org/10.1007/BF00685071

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