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An epithelial cyst of the spinal cord. An electron microscopic study

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Summary

The fine structure of an intradural and extramedullary cyst compressing the spinal cord was examined. The cyst was lined by a single epithelial layer of both ciliated and non-ciliated cells. The non-ciliated cells differ from the former by the presence of secretory granules and a surface coating as well as other characteristics. The epithelial layer was bordered by a basement membrane and prominent interdigitation was found along the lateral borders. The origin of these cells is unknown but the similarity between them and the epithelium of the respiratory tract is noted.

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Literature

  • Bennett, H. S.: Morphological aspects of extracellular polyasaccharides. J. Histochem. Cytochem.11, 14–23 (1963).

    Google Scholar 

  • Brightman, M. W., Palay, S. L.: The fine structure of ependyma in the brain of the rat. J. Cell Biol.19, 415–439 (1963).

    Google Scholar 

  • Cancilla, P. A., Zimmerman, H. M., Becker, N. H.: A histochemical and fine structure study of the developing rat choroid plexus. Acta neuropath. (Berl.)6, 188–200 (1966).

    Google Scholar 

  • Coxe, W. S., Luse, S. A.: Colloid cyst of third ventricle. An electron microscopic study. J. Neuropath. exp. Neurol.23, 431–445 (1964).

    Google Scholar 

  • Elsberg, C. A.: Tumors of the spinal cord and the symptoms of irritation and compression of the spinal cord and nerve roots: Pathology, Symptomatology, Diagnosis and Treatment. New York: Paul B. Hoeber 1925.

    Google Scholar 

  • Farbman, A. I.: Plasma membrane changes during keratinization. Anat. Rec.156, 269–282 (1966).

    Google Scholar 

  • Harriman, D. G. F.: An intraspinal enterogenous cyst. J. Path. Bact.75, 413–419 (1958).

    Google Scholar 

  • Hirano, A., Zimmerman, H. M.: Some new cytological observations of the normal rat ependymal cell. Anat. Rec.158, 293–301 (1967).

    Google Scholar 

  • —— Levine, S.: The fine structure of cerebral fluid accomulation. Reaction of spendyma to implantation of cryptococcal polysaccharide. J. Path. Bact.91, 149–155 (1966).

    Google Scholar 

  • Hoenig, E. M., Ghatak, N. R., Hirano, A., Zimmerman, H. M.: Multilocuated cystic tumor of the ehoroid plexus of the fourth ventricle. Case report. J. Neurosurg.27, 574–579 (1967).

    Google Scholar 

  • Hoffman, G. T.: Cervical arachnoidal cyst — Report of a 6 year old negro male with recovery from quadriplegia. J. Neurosurg.17, 327–330 (1960).

    Google Scholar 

  • Hughes, T.: Pathology of the spinal cord. London: Lloyd-Luke Ltd. 1966.

    Google Scholar 

  • Hyman, I., Hamby, W. B., Sanes, S.: Ependymal cyst of the cervico-dorsal region of the spinal cord. Arch. Neurol. Psychiat. (Chic.)40, 1005–1012 (1938).

    Google Scholar 

  • Ito, S.: The enteric surface coat on cat intestinal microvilli. J. Cell Biol.27, 475–491 (1965).

    Google Scholar 

  • Knight, G., Griffiths, T., Williams, L.: Gastrocytoma of spinal cord. Brid. J. Surg.42, 635–638 (1955).

    Google Scholar 

  • Kubie, L. S., Fulton, J. F.: A clinical and pathological study of two teratomatous cysts of the spinal cord, containing mucus and ciliated cells. Surg. Gynec. Obstet.47, 297–311 (1928).

    Google Scholar 

  • Ley, A., Jr., Marti, A.: Intramedullary hydatid cyst. Case Report. J. Neurosurg.33, 457–459 (1970).

    Google Scholar 

  • Moore, M. T., Book, M. H.: Congenital cervical ependymal cyst. Report of a case with symptoms precipitated by injury. J. Neurosurg.24, 558–561 (1966).

    Google Scholar 

  • Nassar, S. I., Correll, J. W., Housepian, E. M.: Intermedullary cystic lesions of the conus medullaris. J. Neurol. Neurosurg. Psychiat.31, 106–109 (1968).

    Google Scholar 

  • Parkinson, D., Childe, A. E.: Colloid cyst of the fourth ventricle. Report of a case of two colloid cysts of the fourth ventricle. J. Neurosurg.9, 404–409 (1952).

    Google Scholar 

  • Porter, K. R., Bonneville, M. A.: Fine structure of cells and tissues. Philadelphia: Lea & Febiger 1968.

    Google Scholar 

  • Rewcastle, N. B., Francoeur, J.: Teratomatous cysts of the spinal cord with “Sex Chromatin” studies. Arch. Neurol. (Chic.)11, 91–99 (1964).

    Google Scholar 

  • Rhaney, K., Barclay, G. P. T.: Enterogenous cysts and congenital diverticula of alimentary canal with abnormalities of vertebral column and spinal cord. J. Path. Bact.77, 457–471 (1959).

    Google Scholar 

  • Russell, D. S., Rubinstein, L. J.: Pathology of tumours of the nervous system. Second edition. London: Edward Arnold Ltd. 1963.

    Google Scholar 

  • Scoville, W. B., Manlapas, J. S., Otis, R. D., Cabieses, F.: Intraspinal enteregenous cyst. J. Neurosurg.20, 704–706 (1963).

    Google Scholar 

  • Shuangshoti, S., Netsky, M. G.: Neuroepithelial (colloid) cysts of the nervous system. Further observation on pathogenesis, location, incidence and histochemistry. Neurology (Minneap.)16, 887–903 (1966a).

    Google Scholar 

  • ——: Histogenesis of choroid plexus in man. Amer. J. Anat.118, 283–315 (1966b).

    Google Scholar 

  • — Roberts, M. P., Netsky, M. G.: Neuroepithelial (colloid cysts). Arch. Path.80, 214–224 (1965).

    Google Scholar 

  • —— Nashold, B. S.: Epithelial cysts related to sella turcica. Proposed origin from neuroepithelium. Arch. Neurol. (Chic.)90, 444–450 (1970).

    Google Scholar 

  • Stochdorph, O.: Zur Abkunft der Foramen-Monroi-Cysten. Nervenarzt34, 226–229 (1963).

    Google Scholar 

  • Tennyson, V. M., Pappas, G. D.: Electron microscopic studies of the developing telencephalic choroid plexus in normal and hydrocephalic rabbits. In: Disorders of the developing nervous system. (W. S. Fields and M. M. Desmond, Eds.), pp. 267–325. Springfield, Ill.: Ch. C. Thomas 1961.

    Google Scholar 

  • ——: An electron microscope study of ependymal cells of the fetal, early postnatal and adult rabbit. Z. Zellforsch.56, 595–618 (1962).

    Google Scholar 

  • Wisoff, H. S., Ghatak, N. R.: Ependymal cyst of the spinal cord. Case report. J. Neurol. Neurosurg. Psychiat. (in press).

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This study was aided by the Sandy Schneider Memorial Fund and the USPHS General Research Support Grant No. RR. 5499.

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Hirano, A., Ghatak, N.R., Wisoff, H.S. et al. An epithelial cyst of the spinal cord. An electron microscopic study. Acta Neuropathol 18, 214–223 (1971). https://doi.org/10.1007/BF00685067

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  • DOI: https://doi.org/10.1007/BF00685067

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