Summary
Insite into the metabolism of the glandular area of the cervix may be obtained through enzyme histochemical investigations. For this purpose the special enzymes of glucose metabolism, fatty acids oxidation, pentose-phosphate metabolism, citric acid cycle as well as the enzymes of the NADH- and NADPH-diaphorase system and amino acids metabolism were investigated. The uniform methode employed permits a form of screening test whereby information may be obtained about the activities of the different enzymes. With exception to one enzyme of glucose metabolism, the alcohol dehydrogenase, and that of amino acids metabolism, glutamic dehydrogenase, all ferments could be demonstrated. Their function is discussed with especial reference to their importance on the cervix glands. Further enzyme histochemical studies during the different periods of life of the female corresponding to earlier functional morphologic studies are anticipated.
Zusammenfassung
Durch enzym-histochemische Untersuchungen an Cervices soll Einblick in den Stoffwechsel des cervicalen Drüsenfeldes gewonnen werden. Hierfür wurden insbesondere die Enzyme des Glucosestoffwechsels, der Fettsäureoxydation, des Pentosephosphatstoffwechsels, des Citronensäurecyclus sowie des NADH- und NADPH-Diaphorese-Systems und des Aminosäurestoffwechsels untersucht. Die einheitliche Nachweistechnik erlaubt in Form eines Art Screening-Tests eine Information über die vorhandenen Aktivitäten der einzelnen Enzyme, wobei — abgesehen von einem Enzym des Glucosestoffwechsels, nämlich der Alkoholdehydrogenase und des Aminosäurestoffwechsels, der Glutamatdehydrogenase — alle Fermente nachgewiesen werden konnten. Auf ihre Wirkung wird im einzelnen insbesondere in bezug auf die Bedeutung im cervicalen Drüsenfeld eingegangen. Weitere enzym-histochemische Untersuchungen in den einzelnen Lebensphasen der Frau sind entsprechend vorangegangener funktioneller morphologischer Studien vorgesehen.
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Walther, G., Hiersche, H.D. Enzym-histochemische Studien am cervicalen Drüsenfeld des Uterus. Arch. Gynak. 213, 187–196 (1972). https://doi.org/10.1007/BF00667674
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DOI: https://doi.org/10.1007/BF00667674