Abstract
Buoyant density fractionation ofDrosophila melanogaster chromatin utilizing low molecular weight molecules such as actinomycin-D to induce changes in buoyant density has been investigated. Fractions of chromatin containing identifiable repeated DNA sequences could be isolated using actinomycin-D as the selective agent. Protein displacement from the chromatin complex was found to be a prerequisite for the observed buoyant density changes.
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Appels, R. Buoyant density fractionation ofDrosophila melanogaster chromatin. Mol Biol Rep 3, 217–222 (1977). https://doi.org/10.1007/BF00643476
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DOI: https://doi.org/10.1007/BF00643476