Abstract
The ionophoric properties of the di-sec-butyl derivatives of dibenzo-18-crown-6 have been studied in natural and model membranes. It has been shown that the di-sec-butyl substituents in the benzene rings of dibenzo-18-crown-6 impart to the cyclopolyether the properties of an ionophore for magnesium. The Mg2+/Ca2+ selectivity of the cyclopolyether investigated was 4.8 according to results obtained on artifical membranes and mitochondria.
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Institute of Biochemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Institute of Bioorganic Chemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 234–239, March–April, 1981.
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Tashmukhamedov, B.A., Gagel'gans, A.I., Shkinev, A.V. et al. 4',4”- and 4',5”-di-sec-butyl-2,3:11,12-dibenzo-18-crown-6 — An ionophore for magnesium in natural and model systems. Chem Nat Compd 17, 189–193 (1981). https://doi.org/10.1007/BF00634745
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DOI: https://doi.org/10.1007/BF00634745