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The immobilization of the enzymeE. coli L-asparaginase on polysaccharides. III. Covalent binding with 3-bromo-2-hydroxypropyldextran

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Abstract

The synthesis of immobilized L-asparaginase on 3-bromo-2-hydroxypropyldextran has been effected. Some physicochemical properties of the preparations obtained have been studied. A stabilizing effect of the modification on the heat stability of the L-asparaginase has been detected. The influence of the bound polymer on the antigenic properties of the enzyme have been established.

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Authors
  1. A. S. Karsakevich
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  2. S. N. Shulichenko
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  3. Yu. I. Shilov
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  4. R. A. Zhagat
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Additional information

Institute of Organic Synthesis, Academy of Sciences of the Latvian SSR, Riga. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 224–228, March–April, 1981.

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Karsakevich, A.S., Shulichenko, S.N., Shilov, Y.I. et al. The immobilization of the enzymeE. coli L-asparaginase on polysaccharides. III. Covalent binding with 3-bromo-2-hydroxypropyldextran. Chem Nat Compd 17, 179–183 (1981). https://doi.org/10.1007/BF00634743

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  • DOI: https://doi.org/10.1007/BF00634743

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