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New data on the mechanism of the Fischer indole synthesis (review)

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Recent data on the mechanism of the rearrangement of arylhydrazones to indoles (the Fischer reaction) are examined. The effect of electronic factors and the acidity of the medium on the rate of the process is discussed. The regioselectivity of the indolization reaction and its quantum-chemical interpretation are analyzed.

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  1. K. A. Timiryazev Moscow Agricultural Academy, 127550, Moscow

    N. M. Przheval'skii, L. Yu. Kostromina & I. I. Grandberg

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  1. N. M. Przheval'skii
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  2. L. Yu. Kostromina
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  3. I. I. Grandberg
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 867–880, July, 1988.

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Przheval'skii, N.M., Kostromina, L.Y. & Grandberg, I.I. New data on the mechanism of the Fischer indole synthesis (review). Chem Heterocycl Compd 24, 709–721 (1988). https://doi.org/10.1007/BF00633160

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