Abstract
The preparation of75Se-adenosyl selenome-thionine is described. Following injection into male rats 63% of the administered label was excreted in 24 h, predominantly in the urine. The remaining activity appeared to have joined the S-adenosyl methionine pool residing mainly in the liver and kidney. The maximum incorporation into the ventral prostate was 2 to 4 h after injection at 0.7% injected dose/g wet weight. These results indicate that75Se-adenosyl selenomethionine is not a suitable radiopharmaceutical for diagnostic scanning of the prostate.
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Eakins, M.N. The distribution of75Se-adenosyl selenomethionine in the rat with observations on its potential as a prostate scanning agent. Eur J Nucl Med 4, 101–103 (1979). https://doi.org/10.1007/BF00626079
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DOI: https://doi.org/10.1007/BF00626079