Abstract
Two-dimensional1H NMR spectroscopy (COSY, NOESY) in combination with the one-dimensional variant has been used to establish the conformation of the molecule of britannin — a sesquiterpene lactone of the ambrosane type. The comparative possibilities of one- and two-dimensional NMR spectroscopies in stereochemical investigations of sesquiterpene lactone with ambrosane skeletons are considered.
Similar content being viewed by others
Literature cited
K. S. Rybalko, V. I. Scheichenko, G. A. Maslova, E. Ya. Kiseleva, and I. A. Gubanov, Khim. Prir. Soedin., 251 (1968).
P. V. Chugunov, V. I. Sheichenko, A. I. Ban'kovskii, and K. S. Rybalko, Khim. Prir. Soedin., 276 (1971).
K. S. Rybalko, Natural Sesquiterpene Lactones [in Russian], Meditsina, Moscow (1978), p. 25.
R. R. Ernst, G. Bodenhausen, and A. Wokaun, Principles of Nuclear Magnetic Resonance in One and Two Dimensions, Clarendon Press, Oxford (1987).
R. A. Bell and J. K. Saunders, Can. J. Chem.,46, 3421 (1968).
J. H. Noggle and R. E. Schirmer, The Nuclear Overhauser Effect, Academic Press, New York (1971), p. 51.
A. A. Bothner-By, Adv. Magn. Reson. Spectrosc.,1, 195 (1965).
H. Booth, Prog. Nucl. Magn. Reson. Spectrosc.,5, 212 (1968).
E. L. Eliel, N. L. Allinger, S. J. Angyal, and G. A. Morrison, Conformational Analysis, Interscience, New York (1965) [Russian translation, Mir, Moscow (1969), p. 254].
Additional information
All-Union Scientific-Research Institute of Medicinal Plants, Moscow. Translated from Khimiya Prirodnykh Soedinenii, Vol. 6, pp. 792–796, November–December, 1989.
Rights and permissions
About this article
Cite this article
Okhanov, V.V., Sheichenko, V.I. & Miroshnikov, A.I. Structure of britannin. Use of two-dimensional1H NMR spectroscopy. Chem Nat Compd 25, 672–676 (1989). https://doi.org/10.1007/BF00598263
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF00598263